Selangor traffic chief Supt Kamaludin Mohamad said the accident involving a superbike occurred at about 2.52pm on Saturday.
Supt Kamaludin said the two victims were identified as Muhammad Asyraf Mohd Naizie and Muhammad Fudail Mazlin, both aged 16.
He said according to a witness, the rider of the motorcycle, which was on the right lane had lost control and grazed the road divider.
The impact flung him onto a tree before he fell back onto the road.
Supt Kamaludin said the pillion rider was also thrown off onto the road due to the collision.
He said both the victims were pronounced dead at the scene by paramedics.
Supt Kamaludin said the victims were sent to the Shah Alam Hospital for post-mortem.
He said the case was being investigated under Section 41 (1) of the Road Transport Act 1987.